Six (6) were reported to have recovered or were recovering (at the time of reporting) after stopping the suspected products, whereas the remaining three (3) did not recover. Out of the nine (9) patients that experienced the adverse reactions, seven (7) were hospitalised. Most of them were also concurrently taking other medications and were reported to have underlying medical conditions, including chronic kidney impairments, diabetes, coronary artery disease (the build-up of plaque in the heart’s arteries that could lead to heart attack). The patients were between 30 to 60 years of age. The adverse reactions were reported to occur as early as six (6) days and up to four (4) months after the consumption of ganoderma-containing products. The reactions reported were increased in creatinine and urea (waste products normally removed by the kidneys) in the blood, acute interstitial nephritis (swelling of a part of the kidneys’ filters) and also worsening of existing kidney impairments. NPRA has received nine (9) local reports of kidney-related adverse reactions suspected to be associated with ganoderma-containing products in the last one (1) year. Nine (9) reports of kidney-related adverse reactions The National Centre for Adverse Drug Reactions Monitoring, NPRA has detected an increase in the number of adverse reaction reports related to consumptions of ganoderma/ lingzhi with 11 cases in the past one (1) year. Lucidum or lingzhi as single ingredients that are available in the tablets, capsules, and powder forms. In Malaysia, there are 81 registered products of G. Lucidum products are available in various forms, such as powders, tablets, capsules and tea. 2 However, there are no clinical studies in humans supporting its effectiveness or safety. 1 It has a long history of use for promoting health and longevity in China, Japan, and other Asian countries. Lucidum is commonly known as lingzhi, and in Japan, reishi or mannentake. Ganoderma lucidum, an oriental fungus, is a large, dark mushroom with a glossy exterior and a woody texture. 4.The National Pharmaceutical Regulatory Agency (NPRA) wishes to advise the public on the risks of kidney-related and liver-related adverse reactions related to ganoderma which is also known as lingzhi or reishi. Although there is no evidence of harm, to ensure safety for mother and baby, it is still not recommended to use unless directed by a doctor. Also pregnant and lactating women are not recommended to use this mushroom. If your platelet count is low, there is an increased risk of bleeding when taking high doses of Ganoderma. Therefore, when using this mushroom, you need to pay close attention to the method of use and dosage. According to some reports, there have been patients with liver toxicity or chronic diarrhea when using powdered Ganoderma. you should also pay attention when combining with Ganoderma lucidum. If you are being treated for diabetes, immune system disorders. For patients with too low or too high blood pressure, there is an increased risk of risks when using Ganoderma lucidum. However, after about 3 - 6 months, this herb can cause allergies on the skin leading to dry skin and affect some organs such as: Mouth Throat Nose Also allergic manifestations can be : Dizziness, rash rash, headache, upset stomach, high bleeding, bloody stools. Dosage of Ganoderma according to researchĪt first, you may not feel the side effects of Ganoderma lucidum to your body. Therefore, scientists need to continue to analyze to come up with more useful studies on the effects of Ganoderma on the body. The effects found in human trials are only marginally beneficial compared to the assumptions about the usefulness of this precious herb. Reducing the risk of catching the flu caused by bacteria Repelling some dangerous diseases of the century Help in cancer treatment Reduce pain and prevent the risk of shingles re-infection Create a strong immune system for patients Reduce stress fatigue Most of the effects have been found in experiments only a few have been tested on humans. In addition, Ganoderma lucidum also has health effects such as: Stability blood pressure Balance cholesterol level Limit the risk of cardiovascular disease Enhance liver and kidney function Prevent respiratory diseases such as asthma. According to some previous studies, the use of Ganoderma lucidum improves problems such as stress, insomnia. Ganoderma or red reishi mushrooms have any effect? This is always a question of first-time users of the product.
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